Kangpu Biopharmaceuticals, a clinical-stage company based in Hefei, China, announced today that the Company has successfully ...

MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...

Scientists at Livzon Pharmaceutical Group Inc., Shanghai Institute of Organic Chemistry and the University of Michigan have identified proteolysis targeting chimeras (PROTACs) comprising an E3 ...

Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, ...

NIH-Led Studies Point to Potential Development of a Cataract Drug – Findings Suggests a Surgery-Free Treatment ...

The growing challenge in cancer therapy lies in overcoming tumor heterogeneity, drug resistance, and associated side effects.

L1, NfL, and t-tau are all promising plasma biomarkers that show sex specific changes in adolescents post sport-related ...

Here, we demonstrate that PP5 is subject to SUMOylation on K430. SUMOylation is a reversible PTM which results from the conjugation of a small ubiquitin-like modifier (SUMO) protein to a lysine ...

Emr also found that ESCRT complexes recognize proteins that are tagged with a molecule called ubiquitin and sends them to the ...