Overall, our findings suggest that these specific SNPs may not be major contributors to ... TMPRSS2 (transmembrane serine protease 2), IFNB1 (interferon beta 1), ISG15 (ubiquitin like modifier), STAT1 ...

Unlike endogenous GHRH, CJC-1295 has a modified structure that resists degradation by dipeptidyl peptidase IV (DPP-IV), potentially ... the dexamethasone-induced expressions of muscle-specific ...

Neurotransmitters are key for synaptic transmission at axon terminals, but their transport modalities remain debated. This ...

In the absence of E2, ASC1 remains non-modified due to its association with the UFM1-specific protease UfSP2. Upon E2 exposure, ERα displaces UfSP2 from ASC1, leading to its UFMylation. This ...

Mice with myeloid-specific deletion of Vangl2 (Vangl2 ΔM ... Mechanistically, NF-κB signaling-induced-Vangl2 recruits E3 ubiquitin ligase PDLIM2 to catalyze K63-linked ubiquitination on p65, which ...

Identification of potent COVID-19 main protease inhibitors by loading of favipiravir on Mg12O12 and Zn12O12 nanoclusters: an in silico strategy for COVID-19 treatment.